Presentation T O30

T O30 (Oral Presentation):
The longitudinal relationship of obesity, major depression and their combination with work performance impairment: The Netherlands study of depression and anxiety

Presented by: Yeshambel T. Nigatu

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Authors

Nigatu YT1, Reijneveld SA1, Schoevers RA2, Penninx BWJH2,3, Bültmann U1

  1. Department of Health Sciences, University Medical Center Groningen, University of Groningen, Groningen
  2. Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen
  3. Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands

Abstract

Background

Obesity and major depression are highly prevalent in the general and working population, posing enormous challenges in the decades to come. The potential separate and combined effects of obesity and major depression in relation to work performance impairment (WPI) have not been studied yet. The aim of this study was to examine the longitudinal relationship of obesity, major depression and their combination with WPI.

Methods

Longitudinal data was collected on N=1726 paid employees selected from an ongoing cohort study, the Netherlands Study of Depression and Anxiety (NESDA) at baseline, 2-year, 4-year and 6-year follow-up. Obesity was defined as a body mass index (BMI) ≥ 30, and waist circumference (WC) of ≥102 cm and ≥88 cm for males and females, respectively. MD was diagnosed with the composite international diagnostic interview (CIDI 2.1) and WPI was assessed with a questionnaire for costs associated with illness (Tic-P). We used generalized estimating equations (GEE) for modeling. Interaction on the additive and multiplicative scale was estimated.

Results

Obesity, abdominal obesity and MD longitudinally gave an increased risk of high WPI (adjusted odds ratio, aOR=1.63; 95% confidence interval, CI: 1.35; 1.96, aOR=1.23; 95%CI: 1.03; 1.48 and aOR=1.35; 95%CI: 1.08; 1.69), respectively. The joint effect of obesity and MD on high WPI was (aOR=2.36; 95%CI: 1.61; 3.44 with a RERI=0.57; 95%CI: -0.46; 1.60, and of abdominal obesity and MD on high WPI was (aOR=1.88 ; 95%CI: 1.40; 2.53 with a RERI= -0.09; 95%CI: -0.79; 0.61. The interaction effect of obesity and MD on high WPI on the multiplicative scale was OR=1.15; 95%CI: 0.71; 1.85.

Conclusions

Obesity and MD are longitudinally associated with high WPI. The joint effect of obesity and MD on high WPI is additive. Hence, obesity and MD act independently with respect to the risk of high WPI.

Schedule Details

Tuesday September 30
15:45 - 17:30 Afternoon Concurrent Sessions (T O25 - T O38 and Seminar 6)
Session: Work Disability trajectories
Room B